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THE MANUFACTURING PROCESS

This program provides the basic knowledge needed to understand manufacturing practices, common equipment used, and provides a thorough explanation of what it takes to make a quality product.

TABLET PRO

Improving manufacturing skills within a company is critical to the success and key to continuous quality improvement. The methodology, documentation and mindset required to meet the needs of our changing industry.

Articles Written by Michael D. Tousey

HOW TABLET QUALITY AFFECTS COATING SUCCESS

High-quality coating begins with high-quality tablets, and no coating can achieve peak adherence unless all the tablets in a batch are uniform. When the substrate is prepared properly, tablet coating quality is predictable. A film coating won’t hide tablet quality problems and will, in fact, likely magnify quality variations, even when they aren’t extreme. This article discusses how variations in tablets—even when in the acceptable range—can affect film coating.

Originally published by Tablets & Capsules

TABLET COATING MUSTS

When it comes to coating tablets there are musts that really count, and then there are the other things. The ability to coat tablets well is often considered more of an art than a science.

Originally published by Pharmaceutical Processing

TABLETTING: RESOLVING TABLET DEFECTS

Tablet defects bedevil many manufacturers. This article outlines some strategies that tablet production experts use to resolve the most common ones, including weight variation, black spots, capping, sticking and picking.

Originally published by Tablets & Capsules

TEN TIPS ON TROUBLESHOOTING TABLETTING

When things go wrong in the compression department, they can go wrong very quickly. Identifying the root cause can be difficult unless certain things have been done up front.

Originally published by Tablets & Capsules

TABLETTING: PREVENTION IS THE BEST CURE FOR TABLET DEFECTS

A hands-on tabletting consultant offers advice to tablet press operators and their supervisors.

Originally published by Tablets & Capsules

TABLETTING: RELYING ON TABLET PRESS TECHNICIANS

Many Companies limit the adjustments that technicians can make to the tablet press during a production run, even though such adjustments are a normal part of tabletting.  This article discusses what adjustments may be necessary and encourages manufacturing managers to support their tablet technicians.

Originally published by Tablets & Capsules

TABLET DESIGN, QUALITY AFFECT COATING QUALITY

The near-total replacement of organic solvents with water in tablet coating solutions is one of the biggest changes to the tablet coating process in the last two decades. While the switch lowered costs and improved safety, it made the process less forgiving and thus increased the need to tightly control solution delivery and process temperature.

Originally published by Tablets & Capsules

MANAGING DOWNTIME

How long does it take to clean a tablet press and ready it for the next production run? It’s a question tablet press manufacturers get all the time.

Originally published by Tablets & Capsules

TABLET COATING BASICS

After making a good tablet, you must often coat it. The coating can have several functions. It can strengthen the tablet, control its release, improve its taste, color it, make it easier to handle and package, and protect it from moisture. This article reviews the basics of tablet coating and describes common tablet coating defects.

Originally published by Tablets & Capsules

TABLET PRESS OPERATION: PREVENTING AND FIXING WEIGHT AND HARDNESS DEFECTS: STRATEGIES FOR PRODUCTION PERSONNEL

This article focuses on the possible causes of variations in tablet weight and tablet hardness and offers advice on preventing and fixing the source of the problems. It also discusses the problems of formulations with too many fines.

Originally published by Tablets & Capsules

TABLET PRESS OPERATION: STICKING AND PICKING: SOME CAUSES AND REMEDIES

Sticking occurs when granules attach themselves to the faces of tablet press punches. Picking is a more specific term that describes product sticking only within the letters, logos, or designs on the punch faces. This article explains the causes of sticking and picking and describes the steps you can take to resolve both problems.

Originally published by Tablets & Capsules

THE GRANULATION PROCESS 101: BASIC TECHNOLOGIES FOR TABLET MAKING

The author offers a primer for choosing the correct granulation process to improve yields, reduce tablet defects, and enhance productivity.

Originally published by Pharmaceutical Technology

OPTIMAL TABLET PRESS OPERATION: MACHINE VS. GRANULATION

To achieve the maximum performance from a tablet press run, operators must learn to distinguish between machine-related issues and granulation-related issues.

Originally published by Pharmaceutical Technology